David T. Rubin MD, FACG, AGAF, FACP, FASGEProfessor of Medicine at University of Chicago
The agenda for this LIVE webinar includes a 40-minute presentation on “Current Updates on the Management of ASUC" and a 20-minute Q&A session with Prof. David T. Rubin.
Ulcerative colitis (UC) is a chronic inflammatory bowel disease that often has wide-ranging disease severity. About 20–30% of UC patients require hospitalization at some point in their disease course for an acute severe flare (ASUC). Although intravenous steroids are the mainstay of therapy, 30–40% of patients will fail to respond to steroids and require progression to second-line therapy with either infliximab (IFX) or cyclosporine (CsA).
These second-line therapies are associated with a significant risk for adverse events and colectomy carries a 5% postoperative mortality risk when done emergently in the hospital setting. Recent insights in comparative effectiveness, provider practice patterns and biologic pharmacokinetics have allowed for enhanced insight into how best to optimize the care of these high-risk patients.
In this presentation, we discuss the latest emerging evidence and the implications of these data on the management of ASUC.
Prof. David T. Rubin is Chief of the Section of Gastroenterology, Hepatology & Nutrition and the Co-Director of the Digestive Diseases Center at The University of Chicago Medicine. Dr. Rubin earned a medical degree with honors at The University of Chicago Pritzker School of Medicine. He completed his residency in internal medicine and fellowships in gastroenterology and clinical medical ethics at the University of Chicago, where he served as Chief Resident and Chief Fellow. Prior to his current appointments, Dr. Rubin served for 11 years as Director of the Gastroenterology, Hepatology and Nutrition fellowship program. He also currently serves as an associate faculty member at the MacLean Center for Clinical Medical Ethics and an associate investigator at the University of Chicago Comprehensive Cancer Center.
Prof. Rubin is a Fellow of the American Gastroenterological Association (AGA), the American College of Gastroenterology (ACG), the American Society for Gastrointestinal Endoscopy (ASGE) and the American College of Physicians (ACP) and an active national member of the Crohn’s & Colitis Foundation (CCF), and is on the Board of Trustees for the ACG. Among numerous awards and honors, Dr. Rubin was chosen by his peers as a member of Best Doctors (recognized for superior clinical ability) and America’s Top Physicians (gastroenterology). Additionally, he twice received the ACG’s Governor’s Award of Excellence in Clinical Research (2003 and 2013), the Cancer Research Foundation Young Investigator’s Award (2004), and the UC Postgraduate Teaching Award in recognition of significant contributions for fellowship education (2006). In 2012, he received the CCF Rosenthal Award, a national leadership award bestowed upon a volunteer who has contributed in an indisputable way to the quality of life of patients and families. He is currently the Chair-elect of the National Scientific Advisory Committee of the CCF. He is an Associate Editor of the journal Gastroenterology and Co-Editor of the ACG On-Line Educational Universe.
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